Muteins of human erythropoietin, the preparation thereof and the use thereof

Patent 5457089 Issued on October 10, 1995. Estimated Expiration Date:

July 6, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

DNA sequences encoding erythropoietin
Patent #: 4703008
Issued on: 10/27/1987
Inventor: Lin

Erythropoietin composition Patent #: 4835260
Issued on: 05/30/1989
Inventor: Shoemaker

Inventors

Assignee

Behringwerke Aktiengesellschaft

Application

No. 272375 filed on 07/06/1994

US Classes:

514/8, Glycoprotein (carbohydrate containing)424/85.1, LYMPHOKINE435/69.4, Hormones and fragments thereof514/1225 or more peptide repeating units in known peptide chain structure

Examiners

Primary: Furman, Keith C.

Attorney, Agent or Firm

Finnegan, Henderson, Farabow, Garrett & Dunner

International Classes

A61K 038/18
A61K 038/19
A61K 038/22
A61K 038/17

Foreign Application Priority Data

1989-07-20 DE

Abstract

The invention relates to muteins of human erythropoietin (EPO) in the carboxyl terminal region which are prepared by means of recombinant DNA techniques. These mutants have advantageous properties in comparison with human wild-type EPO.

Other References

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