Crosslinked anion exchange particles and method for producing the particles
Patent 5453429 Issued on September 26, 1995. Estimated Expiration Date: 
February 6, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 6, 2015. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3383281 3692895 Ionene modified small polymeric beads Patent #: 4046750 InventorsAssigneeApplicationNo. 384099 filed on 02/06/1995US Classes:514/288, Ring carbon is shared by three of the cyclos424/78.1, Ion exchange resin424/78.12, Adsorbate or treating agent contains nitrogen424/497, Containing solid synthetic polymers514/554, Amine addition salt of the acid514/570, Carboxy or salt thereof only attached indirectly to the benzene ring522/173, Processes of preparing a solid polymer from at least one nitrogen containing monomer; or compositions therefore526/310, From nitrogen containing monomer other than acrylonitrile or methacrylonitrile526/328.5With additional monomerExaminersPrimary: Acquah, Samuel A.Attorney, Agent or FirmInternational ClassA01N 043/42AbstractNew bile acid sequestrant polymer compositions and a process for preparing the polymers in particulate form, preferably in spherical form, are described. The polymer particles are prepared by crosslinking an amine-containing polymer with an amount of a polyfunctional amine-reactive compound sufficient to crosslink the polymer so that it is essentially water insoluble and has bile acid sequestering efficacy greater than that of cholestyramine, preferably greater than about three times the efficacy of cholestyramine. A preferred polymerization process involves suspension polymerization of water-soluble amine-containing monomers, such as dialkylaminoalkyl (meth)acrylate esters and dialkylaminoalkyl (meth)acrylamides, in the presence of polyfunctional amine-reactive compounds, such as substituted dihaloalkanes. Pharmaceutical compositions containing the bile acid sequestrant polymer particles and a method for lowering blood cholesterol levels using the pharmaceutical compositions are also described.Field of SearchRing carbon is shared by three of the cyclosAmine addition salt of the acid Carboxy or salt thereof only attached indirectly to the benzene ring Ion exchange resin Adsorbate or treating agent contains nitrogen Containing solid synthetic polymers Processes of preparing a solid polymer from at least one nitrogen containing monomer; or compositions therefore From nitrogen containing monomer other than acrylonitrile or methacrylonitrile With additional monomer | |
