Supported drugs with increased dissolution rate, and a process for their preparation
Patent 5449521 Issued on September 12, 1995. Estimated Expiration Date: 
February 28, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 28, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3079303 3089824 3328256 3499784 Method of treatment of medicines Injectable compositions, nanoparticles useful therein, and process of manufacturing same Granulation process Pharmaceutical composition Compositions containing ibuprofen Patent #: 4837031 InventorAssigneeApplicationNo. 203034 filed on 02/28/1994US Classes:424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/491, Containing proteins and derivatives424/493, Containing polysaccharides (e.g., sugars)424/497, Containing solid synthetic polymers424/500, Contains natural gums and resins424/501Contains solid synthetic resinExaminersPrimary: Kishore, Gollamudi S.Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/14Foreign Application Priority Data1988-11-28 ITAbstractSupported drugs with an increased dissolution rate, prepared by a process comprising mixing the drug with the support material under dry conditions, co-grinding the mixture in a mill with its grinding chamber saturated with the vapour of one or more solvents able to solubilize the drug or to be adsorbed on the surface of the support material, vacuum-drying the product obtained, and sieving. The drugs obtained in this manner have a reduced heat of fusion, a reduced melting point, an increased dissolution rate and an increased solubilization kinetics.Field of SearchParticulate form (e.g., powders, granules, beads, microcapsules, and pellets)Coated (e.g., microcapsules) Containing polysaccharides (e.g., sugars) Cellulose derivatives Ethyl cellulose Containing natural gums/resins Containing solid synthetic polymers Contains proteins or derivative or polysaccharides or derivative Contains natural gums and resins Contains solid synthetic resin SOLID SYNTHETIC ORGANIC POLYMER AS DESIGNATED ORGANIC ACTIVE INGREDIENT (DOAI) Heavy metal or compound thereof Aluminum, calcium or magnesium element, or compound containing Gas or vapor | |
