U.S. patents available from 1976 to present.
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Dopamine and noradrenergic reuptake inhibitors in treatment of schizophrenia

Patent 5447948 Issued on September 5, 1995. Estimated Expiration Date: Icon_subject September 5, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method and pharmaceutical composition for the treatment of schizophrenia
Patent #: 5177081
Issued on: 01/05/1993
Inventor: Kaminski

Phenoxyphenyl derivatives, compositions and methods of use thereof Patent #: 5190965
Issued on: 03/02/1993
Inventor: Ruigt, et al.

Inventors

Application

No. 880127 filed on 05/07/1992

US Classes:

514/393, Polycyclo ring system having the diazole ring as one of the cyclos514/327Chalcogen bonded directly to ring carbon of the piperidine ring

Examiners

Primary: Henley, III, Raymond
Assistant: Jarvis, William R. A.

Attorney, Agent or Firm

International Classes

A61K 031/415
A61K 031/445

Abstract

Mazindol and other dopamine and/or noradrenergic reuptake inhibitors are effective to treat negative symptoms in schizophrenia.

Other References

  • Delwaide et al., "Mazindol in the Treatment of Parkinson's Disease," Arch. Neurol., vol. 40, pp. 788-790 (Dec. 1983)
  • Krumholz et al., "Clinical Evaluation of Mazindol in Chronic Schizophrenics," Current Therapeutic Research, vol. 12, No. 9, pp. 609-610 (Sep. 1970)
  • Joyce et al., Biosis, AN 89:162887, BA87:84988, 1988
  • Chinaglia et al., Medline, AN 93063820, 1992
  • Hirai et al., Medline, AN 89126127, 198
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