U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Extended release pharmaceutical formulations

Patent 5445829 Issued on August 29, 1995. Estimated Expiration Date: Icon_subject August 29, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3119742

3458622

3623997

Fungimycin compositions
Patent #: 4000254
Issued on: 12/28/1976
Inventor: Gordon ,   et al.

New oral form of medicament and a method for producing it
Patent #: 4083949
Issued on: 04/11/1978
Inventor: Benedikt

Sustained release tablet formulations
Patent #: 4140755
Issued on: 02/20/1979
Inventor: Sheth ,   et al.

Sustained release indomethacin
Patent #: 4173626
Issued on: 11/06/1979
Inventor: Dempski ,   et al.

Controlled release tablet
Patent #: 4252786
Issued on: 02/24/1981
Inventor: Weiss ,   et al.

Method and composition for the preparation of controlled long-acting pharmaceuticals
Patent #: 4259314
Issued on: 03/31/1981
Inventor: Lowey

Sustained release pharmaceutical compositions
Patent #: 4309405
Issued on: 01/05/1982
Inventor: Guley ,   et al.

More ...

Inventors

Application

No. 898539 filed on 06/15/1992

US Classes:

424/480, Cellulose or derivative424/457, Sustained or differential release424/458, Containing discrete coated particles pellets, granules, or beads424/459, Organic coatings424/460, Containing proteins or derivatives thereof (e.g., gelatin, etc.)424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/468, Sustained or differential release type424/474, Coated pills or tablets424/475, Organic coatings424/494, Cellulose derivatives424/497, Containing solid synthetic polymers427/2.21Retarded or controlled-release layer produced (e.g., enteric)

Examiners

Primary: Krass, Frederick
Assistant: Harrison, Robert H.

Attorney, Agent or Firm

Foreign Patent References

  • 763735 BE. 03/13/1991
  • 1183665 CA. 03/13/1985
  • 0103991 EP. 03/13/1984
  • 0122077 EP. 10/13/1984
  • 0325843 EP. 08/13/1989
  • 55-45601 JP. 03/13/1980
  • 1182124 GB. 02/13/1970
  • 1245467 GB. 09/13/1971
  • 2098867 GB. 12/13/1982
  • 2141342 GB. 12/13/1984
  • 2159715 GB. 12/13/1985
  • 86/01717 WO. 03/13/1986

International Classes

A61K 009/56
A61K 009/30

Abstract

An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to about 50% of an immediate release particle containing a drug, inert substrate and binder, coated with talc and up to 100% of an extended release particle comprising the immediate release particle coated with a dissolution modifying system containing plasticizers and a film forming agent.

Other References

  • The Dow Chemical Company "Formulating for Controlled Release with METHOCEL Cellulose Ethers" (1987
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