Technetium-99m labeled peptides for imaging
August 22, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesBifunctional chelating agents Technetium chelates Metal chelate conjugated monoclonal antibodies Homocysteine and homocysteinamide derivatives Process for preparing certain sulfophenethylsiloxanes Coupling agents for joining radionuclide metal ions with biologically useful proteins Imaging tissue sites of inflammation Method for radiolabeling proteins Molecular recognition units Technetium-99m labeled somatostatin-derived peptides for imaging InventorsAssigneeApplicationNo. 807062 filed on 11/27/1991US Classes:424/1.41, Attached to lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interferon, interleukin, macrophage factor, colony stimulating factor, erythropoietin); derivative thereof424/1.69, Attached to peptide or protein of 2+ amino acid units (e.g., dipeptide, folate, fibrinogen, transferrin, sp. enzymes); derivative thereof930/280Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resinExaminersPrimary: Geist, GaryAssistant: Chapman, Lara E. Attorney, Agent or FirmForeign Patent References
International ClassA61K 051/08AbstractThe invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention provides peptides which bind Tc-99m and which can be targeted to specific sites within a mammalian body.Other References
Field of SearchAttached to peptide or protein of 2+ amino acid units (e.g., dipeptide, folate, fibrinogen, transferrin, sp. enzymes); derivative thereofAttached to lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interferon, interleukin, macrophage factor, colony stimulating factor, erythropoietin); derivative thereof Of side chain or sulfur containing group Chemical aftertreatment, e.g., acylation, methylation, etc. PEPTIDES OF 3 TO 100 AMINO ACID RESIDUES Technetium containing (At. No. 43; Tc) Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin Containing sulfur (See note 4) Containing heavy metal or salt thereof |
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