U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Treatment of lower urinary tract disorders with selective norepinephrine uptake inhibitors

Patent 5441985 Issued on August 15, 1995. Estimated Expiration Date: Icon_subject May 13, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Arloxyphenylpropylamines
Patent #: 4314081
Issued on: 02/02/1982
Inventor: Molloy ,   et al.

3-aryloxy-3-substituted propanamines Patent #: 4956388
Issued on: 09/11/1990
Inventor: Robertson, et al.

Inventor

Assignee

Application

No. 061335 filed on 05/13/1993

US Classes:

514/646Benzene ring containing

Examiners

Primary: Cintins, Marianne M.
Assistant: MacMillan, Keith D.

Attorney, Agent or Firm

Foreign Patent References

  • 052492 EP 05/12/1982
  • 288188 EP 10/12/1988
  • 367040 EP 05/12/1990

International Class

A61K 031/135

Abstract

This invention provides a method of treating lower urinary tract disorders in mammals employing compounds which inhibit norepinephrine reuptake and having negligible anticholinergic effect.

Other References

  • Wong et al., J. Pharmacology and Experimental Therapeutics, 222(1), 61-65 (1982)
  • The Merck Manual pp. 1639-1641, published by Merck & Co., Inc., Rahway, N.J. 1985
  • Rushton, J. Pediatrics, 114(2), 691-696 (1989)
  • Shaffer et al., Neuropharm., 18, 33 (1979)
  • Lipshultz et al., Invest. Urology, 11, 182 (1973)
  • Khanna et al., Urology, 6, 48 (1975)
  • Zerbe et al., J. Pharmacol. Ex. Ther., 232(1), 139-143 (1985)
  • Bertilsson et al., Clin. Pharmacol. Ther., 40(3), 261-267 (1986)
  • Cohen et al., J. Pharmacol. Exp. Ther., 248(3), 1063-1068 (1989)
  • Goodman et al., Pharmacological Basis of Therapeutics7th ed., Macmillan Pub. Co., New York Apr. 198
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