Patent References 3591584 Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor Topical anti-inflammatory compositions Antiinflammatory compositions and methods Benzothiazine dioxide derivatives Patent #: 5081118 InventorsApplicationNo. 181510 filed on 01/14/1994US Classes:514/226.5, One of the cyclos is a 1,2-thiazine (e.g.,1,2-benzothiazines, etc.)514/224.2, Polycyclo ring system having the six-membered hetero ring as one of the cyclos (e.g., 1,3- and 1,4- benzothiazines, etc.)514/663, Acyclic514/667, C-O-group containing514/669PolyhydroxyExaminersPrimary: Dees, Jose G.Assistant: Jones, Dwayne C. Attorney, Agent or FirmInternational ClassA61K 031/54AbstractThe composition contains: an antiinflammatory effective amount of piroxicam; an amount of tetrahydroxypropylethylenediamine sufficient to solubilize the piroxicam in the composition; an amount of C2 -C6 alkylene glycol, or mixture thereof, sufficient to detackify the composition and provide humectancy; about 0.2% to about 2% carbomer; about 30% to about 60% C2 -C4 alkanol; and water qs to 100%. Hydroxypropylcellulose can be added to the composition. | |