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US Patent 5436241 - Topical anti-inflammatory compositions containing piroxicam

US Patent Issued on July 25, 1995
Estimated Patent Expiration Date: Icon_subject January 14, 2014Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

The composition contains: an antiinflammatory effective amount of piroxicam; an amount of tetrahydroxypropylethylenediamine sufficient to solubilize the piroxicam in the composition; an amount of C2 -C6 alkylene glycol, or mixture thereof, sufficient to detackify the composition and provide humectancy; about 0.2% to about 2% carbomer; about 30% to about 60% C2 -C4 alkanol; and water qs to 100%. Hydroxypropylcellulose can be added to the composition.

Inventors

Application

No. 181510 filed on 01/14/1994

US Classes:

514/226.5, One of the cyclos is a 1,2-thiazine (e.g.,1,2-benzothiazines, etc.)514/224.2, Polycyclo ring system having the six-membered hetero ring as one of the cyclos (e.g., 1,3- and 1,4- benzothiazines, etc.)514/663, Acyclic514/667, C-O-group containing514/669Polyhydroxy

Field of Search

514/224.2, Polycyclo ring system having the six-membered hetero ring as one of the cyclos (e.g., 1,3- and 1,4- benzothiazines, etc.)514/226.5One of the cyclos is a 1,2-thiazine (e.g.,1,2-benzothiazines, etc.)

Examiners

Primary: Dees, Jose G.
Assistant: Jones, Dwayne C.

Attorney, Agent or Firm

US Patent References

3591584, 4582831, Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor
Issued on: 04/15/1986
Inventor: Robertson
4678666, Topical anti-inflammatory compositions
Issued on: 07/07/1987
Inventor: Nozawa ,   et al.
4994457, Antiinflammatory compositions and methods
Issued on: 02/19/1991
Inventor: Crawford, et al.
5081118Benzothiazine dioxide derivatives
Issued on: 01/14/1992
Inventor: Braisted, et al.

International Class

A61K 031/54

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