U.S. patents available from 1976 to present.
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Antibacterial fatty acid compositions

Patent 5434182 Issued on July 18, 1995. Estimated Expiration Date: Icon_subject May 3, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Inactivation of viruses in labile protein-containing compositions using fatty acids
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Antimicrobial medical glove
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More ...

Inventors

Application

No. 058056 filed on 05/03/1993

US Classes:

514/546, ZC(=O)OY, wherein Z is an acyclic radical bonded to the C=O by a carbon and Y is an organic radical bonded to the oxygen by a carbon514/547, Compound contains two or more C(=O)O groups514/558Higher fatty acid or salt thereof

Examiners

Primary: Fay, Zohreh

Attorney, Agent or Firm

Foreign Patent References

  • 21504 EP. 01/12/1981
  • 0068552 EP. 01/12/1983
  • 289204 EP. 11/12/1988
  • 57-106618 JP. 07/12/1982
  • 63-57549 JP. 03/12/1988
  • 2181349 GB. 04/12/1987
  • 8809655 WO. 12/12/1988

International Classes

A61K 031/22
A61K 031/225
A61K 031/20

Abstract

This invention is directed to antibacterial activity of fatty acids and monoglycerides. More particularly, this invention is directed to the killing of bacteria by fatty acids and monoglycerides. The invention is also directed to antibacterial pharmaceutical compositions consisting essentially of inert pharmaceutical carrier and an antibacterial effective amount of one or more compounds selected from the group consisting of fatty acids and monoglycerides thereof, fatty alcohols, and ethers and lysophosphatidylcholine derivatives.

Other References

  • Antimicrobial Agents and Chemotherapy, vol. 31, No. 1, Jan. 1987, pp. 27-31; H. Thormar et al
  • Journal of Dairy Science, vol. 59, No. 7, Jul. 1976, pp. 1203-1214, R. G. Jensen et al
  • Archives of Virology, vol. 66, 1980, pp. 301-307, Springer-Verlag; A. Kohn et al.: "Unsaturated free fatty acids inactivate animal enveloped viruses"
  • Microbios Letters, vol. 35, 1987, pp. 71-78, The Faculty Press, Cambridge, GB; V. A. Merchant et al.: "Unsaturated free fatty acid inhibition of herpes simplex virus"
  • Antimicrobial Agents and Chemotherapy, vol. 15, No. 1, Jan. 1979, pp. 67-73; J. Sands et al.: "Extreme sensitivity of enveloped viruses, including herpes simplex, to long-chain unsaturated monoglycerides and alcohols"
  • Antimicrobial Agents and Chemotherapy, vol. 18, No. 6, Dec. 1980, pp. 962-968; A. Kohn et al.: "Interaction of polyunsaturated fatty acids with animal cells and enveloped viruses"
  • Food Chem., vol. 4, No. 4, 1979, pp. 251-258, Applied Science Publishers Ltd. GB; G. Poli et al.: "Virucidal activity of organic acids"
  • Saheb et al., Chemical Abstracts, 90:67131v (1974)
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  • G. A. Loslonsky et al., Maternal-Neonatal Interactions and Human Breast Milk in Reproductive Immunology, N. Gleicher (ed.), New York, Allan R. Riss, 1981, pp. 171-182
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  • Sarker et al., Effect of Human Milk on the Mouse Mammary Tumor Virus, Cancer Res., 1973, vol. 33, pp. 626-62
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