Separation of polynucleotides using supports having a plurality of electrode-containing cells
Patent 5434049 Issued on July 18, 1995. Estimated Expiration Date: 
February 24, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 24, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesElectroelution of macromolecules Electrochemical methods of assay DNA probe diffraction assay and reagents Patent #: 5089387 InventorsAssigneeApplicationNo. 021667 filed on 02/24/1993US Classes:435/6, Involving nucleic acid422/68.1, Means for analyzing liquid or solid sample422/101, Including means for separating a constituent; e.g., filter, condenser, extractor, etc.436/72, SILICON CONTAINING436/94, Saccharide (e.g., DNA, etc.)436/807, APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.)436/809, Multifield plates or multicontainer arrays536/25.4Separation or purification of polynucleotides or oligonucleotidesExaminersPrimary: Parr, MargaretAssistant: Horlick, Kenneth R. Attorney, Agent or FirmForeign Patent References
International ClassesC12Q 001/68G01N 033/48 Foreign Application Priority Data1992-02-28 JPAbstractA method for simultaneously detecting a plurality of target polynucleotides in a sample on a single reaction chip and a method for separating a plurality of target polynucleotides are provided. On the reaction chip are arranged a plurality of independent cells for capturing different target polynucleotides. Different probes are immobilized onto the individual cells, and labeled probes detect the cells where the target polynucleotides are captured, thereby analyzing the species of the captured target polynucleotides. Also, the individual cells function as electrodes to elute the captured target polynucleotides therethrough, thereby separating a plurality of the target polynucleotides.Field of SearchInvolving nucleic acidSaccharide (e.g., DNA, etc.) SILICON CONTAINING APPARATUS INCLUDED IN PROCESS CLAIM (E.G., PHYSICAL SUPPORT STRUCTURES, ETC.) Multifield plates or multicontainer arrays Separation or purification of polynucleotides or oligonucleotides Including means for separating a constituent; e.g., filter, condenser, extractor, etc. Means for analyzing liquid or solid sample |
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