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Method and apparatus to characterize ultrasonically reflective contrast agents

Patent 5433207 Issued on July 18, 1995. Estimated Expiration Date: Icon_subject November 15, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
Patent #: 5215680
Issued on: 06/01/1993
Inventor: D'Arrigo

Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
Patent #: 5230882
Issued on: 07/27/1993
Inventor: Unger

Methods of and systems for examining tissue perfusion using ultrasonic contrast agents Patent #: 5255683
Issued on: 10/26/1993
Inventor: Monaghan

Inventor

Application

No. 153930 filed on 11/15/1993

US Classes:

600/458Contrast enhancement

Examiners

Primary: Manuel, George

International Class

A61B 008/00

Abstract

A method and apparatus for characterizing the time and frequency response of an ultrasonically reflective contrast agent is disclosed. An ultrasonically reflective contrast agent is injected, under constant pressure, into a fluid flowing through a pump flow circuit. The fluid and the ultrasonically reflective contrast agent are uniformly mixed in a mixing chamber, and the uniform mixture is passed through a contrast agent chamber. The contrast agent chamber is acoustically and axially interposed between an ultrasonic transducer chamber and an acoustic isolation chamber. A pulse of ultrasonic energy is transmitted into the contrast agent chamber from the ultrasonic transducer chamber. An echo waveform is received from the ultrasonically reflective contrast agent, and it is analyzed to determine the time and frequency response of the ultrasonically reflective contrast agent.

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