U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Tricyclic compounds and method for treating allergic diseases

Patent 5432192 Issued on July 11, 1995. Estimated Expiration Date: Icon_subject October 1, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

5H Dibenzo (a,d) cycloheptene, 10,11 dihydro, 5(1-halo-3-dimethylaminoprop-1-ylidene) derivatives
Patent #: 3991103
Issued on: 11/09/1976
Inventor: Barton ,   et al.

Tricyclic antidepressant conjugates with antigens and enzymes
Patent #: 4629691
Issued on: 12/16/1986
Inventor: Collins ,   et al.

Reagents and methods for the quantification of total doxepins in biological fluids Patent #: 5332661
Issued on: 07/26/1994
Inventor: Adamczyk, et al.

Inventors

Assignee

Application

No. 122603 filed on 10/01/1993

US Classes:

514/450, The hetero ring has at least seven members514/454, Tricyclo ring system having the hetero ring as one of the cyclos514/510, Polycyclo ring system514/567, Benzene ring nonionically bonded549/354Polycyclo ring system having the hetero ring as one of the cyclos

Examiners

Primary: Dentz, Bernard

Attorney, Agent or Firm

International Classes

A61K 031/335
C07D 313/12

Foreign Application Priority Data

1991-04-05 JP

Abstract

Tricyclic compounds represented by the following formula: ##STR1## wherein X represents --CH=CH--, --CH2 O--, or --O--;R1 represents a lower alkyl group,R2 represents a hydrogen atom or a lower alkyl group; andn represents an integer of from 1 to 5, pharmacologically acceptable salts thereof, and a method for preparing the same. The present compounds have anti-allergic and anti-histaminic activities and reduced side effects, and are useful as anti-allergic agents and anti-histaminic agents.

Other References

  • Hubbard et al., J. of Pharmaceut. Sciences, 67 (11), pp. 1571-1578 (1978
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