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Ultrasonic contrast agents for color Doppler imaging

Patent 5425366 Issued on June 20, 1995. Estimated Expiration Date: Icon_subject June 7, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Ultrasonic image enhancement
Patent #: 4276885
Issued on: 07/07/1981
Inventor: Tickner ,   et al.

Variable frequency gas-bubble-manipulating apparatus and method
Patent #: 4689986
Issued on: 09/01/1987
Inventor: Carson ,   et al.

Ultrasonic imaging agent and method of preparation
Patent #: 4774958
Issued on: 10/04/1988
Inventor: Feinstein

Ultrasonic color doppler diagnostic apparatus Patent #: 5215093
Issued on: 06/01/1993
Inventor: Miyazaki, et al.

Inventors

Assignee

Application

No. 072748 filed on 06/07/1993

US Classes:

600/458Contrast enhancement

Examiners

Primary: Jaworski, Francis J.

Attorney, Agent or Firm

Foreign Patent References

  • 1232837 CA. 02/12/1988
  • 1239092 CA. 07/12/1988
  • 0052575 EP. 05/12/1982
  • 0077752 EP. 04/12/1983
  • 0122624 EP. 10/12/1984
  • 0123235 EP. 10/12/1984
  • 0224934 EP. 06/12/1987
  • 0327490 EP. 08/12/1989
  • 0441468 EP. 08/12/1991
  • 0484181 EP. 05/12/1992
  • 3803972 DE. 08/12/1989
  • WO89/06978 WO. 08/12/1989
  • WO91/15999 WO. 10/12/1991
  • WO93/00991 WO. 01/12/1993

International Class

A61B 008/00

Foreign Application Priority Data

1988-02-05 DE

Abstract

The invention relates to a method for obtaining an ultrasonic image of a patient with ultrasonic color Doppler modality with microparticulate ultrasonic contrast agents in regions where the ultrasonic contrast agents are essentially motionless.

Other References

  • Becher et al., "Improved Sensitivity of Color Doppler by SH U 454", The American Journal of Cardiology, vol. 64, No. 5 (Aug. 1, 1989), pp. 374-377
  • R. Omoto et al., "The Development of Real-Time Two-Dimensional Doppler Echocardiography and Its Clinical Significance in Acquired Valvular Diseases With Special Reference to the Evaluation of Valvular Regurgitation", Jpn. Heart J., vol. 25, No. 3, pp. 325-340 (May 1984)
  • W. J. Bommer et al., "Real.varies.Time Two-Dimensional Color-Flow Doppler: Enhanced Doppler Flow Imaging in the Diagnosis of Cardiovascular Disease", Am. J. Cardiol., vol. 49, p. 944 (Mar. 1982), abstr
  • K. Miyatake et al., "Clinical Applications of a New Type of Real-Time Two-Dimensional Doppler Flow Imaging System", Am. J. Cardiol., vol. 54, pp. 857-868 (Oct. 1, 1984)
  • J. Roelandt, "Contrast Echocardiography", Ultrasound in Med. & Biol., vol. 8, No. 5, pp. 471-492 (1982)
  • Gramiak, "Echocardiography of the Aortic Root", Invest. Radiol., vol. 3 (Sep.-Oct. 1968), pp. 356-366
  • Ophir et al., "Ultrasonic Backscatter From Contrast Producing Collagen Microspheres", Ultrasonic Imaging, vol. 2, pp. 66-67 (1980)
  • Ophir et al., "Aqueous Solutions as Potential Ultrasonic Contrast Agents", Ultrasonic Imaging, vol. 1, pp. 265-279 (1979)
  • Tyler et al., "In-vivo Enhancement of Ultrasonic Image Luminance by Aqueous Solutions with High Speed of Sound", Ultrasonic Imaging, vol. 3, pp. 323-329 (1981)
  • Mattrey et al., "Ultrasonic Enhancement of Myocardial Infarction with Perfluorocarbon Compounds in Dogs", Am. J. Cardiol., vol. 54, pp. 206-210 (Jul. 1, 1984
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