Method for the manufacture of a controlled release solid unit dosage form
December 10, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProlonged release therapeutic compositions based on hydroxypropylmethylcellulose Novel oral preparations Process for preventing agglomeration of powders by using triethylenediamine polymers Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants Controlled release dosage form comprising different cellulose ethers Slow-releasing granules and long acting mixed granules comprising the same Annealed coats Pharmaceutical ion exchange resin composition Patent #: 5071646 InventorAssigneeApplicationNo. 166167 filed on 12/10/1993US Classes:424/490, Coated (e.g., microcapsules)424/480, Cellulose or derivative424/484, Matrices424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/494Cellulose derivativesExaminersPrimary: Page, Thurman K.Assistant: Benston, William E. Jr. Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/16Foreign Application Priority Data1990-12-07 SEAbstractA method for the manufacture of oral controlled release dosage units containing hydroxypropyl methylcellulose wherein the aqueous granulation is performed in the presence of one or more solutes, which inhibit gel formation during the granulation but allows the formation of a gel when administered orally. Also the new dosage units prepared according to the invention are included.Other References
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