Biomedical method and apparatus for controlling the administration of therapy to a patient in response to changes in physiologic demand
Apparatus and method for adjusting heart/pacer rate relative to ejection time to obtain a required cardiac output
Method and apparatus including a sliding insulation lead for cardiac assistance
Physiologic control of pacemaker rate using pre-ejection interval as the controlling parameter
Pacing system and method for cardiac pacing as a function of determined myocardial contractility
Multiple monopolar system and method of measuring stroke volume of the heart
Muscle fitness detection by colorimetry
Muscle stimulator with variable duty cycle
Rate adaptive pacemaker controlled by ejection fraction
ApplicationNo. 243069 filed on 05/16/1994
US Classes:607/18, Plural sensed conditions607/3, Combined with nonelectrical therapy607/23, Blood pressure607/24Stroke volume
ExaminersPrimary: Kamm, William E.
Assistant: Schaetzle, Kennedy J.
Attorney, Agent or Firm
International ClassA61N 001/365
AbstractAn implantable monitor/stimulator is disclosed that monitors and assesses indices of cardiac function, including the strength and timing of cardiac contraction, then automatically executes a physician-selected mode of therapy. It accomplishes this by assessing impedance, electrocardiogram, and/or pressure measurements, then calculating various cardiac parameters. The results of these calculations may be stored within the device, telemetered to an external monitor or display and/or may be used by the physician to determine the mode of therapy to be chosen. If indicated, therapy is administered by the device itself or by telemetering control signals to various peripheral devices for the purpose of enhancing either contraction or relaxation of the heart. The cardiac parameters that are calculated all provide an assessment of level of cardiac function by monitoring changes in ventricular filling and ejection or by calculating isovolumic phase indices of heart contraction. Examples of such parameters are ejection fraction, cardiac output, stroke work, and/or various pressure-volume relationships. These parameters determine the mode of therapy that will be selected by a physician. Choices of therapy include several forms of pacing of cardiac or skeletal muscle, and telemetry to implanted or external units for drug infusion or for monitoring by a central data system.
Field of SearchCombined with nonelectrical therapy
Electrical therapeutic systems
Heart rate regulating (e.g., pacing)
Parameter control in response to sensed physiological load on heart
Plural sensed conditions
CARDIAC AUGMENTATION (PULSATORS, ETC.)
With condition responsive means