U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method and apparatus for localization and spectroscopy of objects using optical frequency modulation of diffusion waves

Patent 5416582 Issued on May 16, 1995. Estimated Expiration Date: Icon_subject February 11, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Re33643

3273458

3400363

3670098

3748470

3802759

3831031

3860821

Infrared gas analysis
Patent #: 3939348
Issued on: 02/17/1976
Inventor: Barrett

Coded imaging systems
Patent #: 3961191
Issued on: 06/01/1976
Inventor: Stoner ,   et al.

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Inventors

Assignee

Application

No. 015983 filed on 02/11/1993

US Classes:

356/484, Having light beams of different frequencies (e.g., heterodyning)600/407, Detecting nuclear, electromagnetic, or ultrasonic radiation600/476Visible light radiation

Examiners

Primary: Hille, Rolf
Assistant: Tran, Minh Loan

Attorney, Agent or Firm

Foreign Patent References

  • 0458601 EP 11/13/1991
  • WO9009003 WO 08/13/1990
  • WO9300045 WO 01/13/1993
  • WO9309423 WO 05/13/1993

International Classes

G01B 009/02
A61B 005/05

Abstract

An apparatus and method for using frequency modulated diffusive photon-density waves propagating through a turbid medium such as tissue for detecting optical properties of objects and for imaging objects within the turbid medium. Frequency modulation enables real time differential measurement of the interaction of different colors with the object when the different colors are chosen such that they react the same with the medium but differently with the object. The method greatly simplifies optical imaging and increases the amount of information which may be obtained about the object.

Other References

  • Knuttel, Improvement of Spatial Resolution in Reflectance Near-Infrared Imaging by Laser-Beam Interference, SPIE, vol. 1640, Jan. 1992
  • Feddersen et al., Digital Parallel Acquistion in Frequency Domain Fluorometry, 60 Rev. Sci. Instrum. 2929, 1989
  • J. Fiskin et al., Diffusion of Intensity Modulated Near-Infrared Light in Turbid Media, Proc. SPIE, 1431, 122-135, 1991
  • Gratton et al., A Continuously Variable Frequency Cross-Correlation Phase Fluorometer With Picosecond Resolution, Biophysical Journal, vol. 44, 315-325, 198
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