U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sustained release composition for oral administration of active ingredient

Patent 5407686 Issued on April 18, 1995. Estimated Expiration Date: Icon_subject April 18, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3133863

3492397

3792157

3854480

Novel drug delivery device
Patent #: 3948254
Issued on: 04/06/1976
Inventor: Zaffaroni

Osmotically driven active agent dispenser
Patent #: 4016880
Issued on: 04/12/1977
Inventor: Theeuwes ,   et al.

Sustained release pharmaceutical composition
Patent #: 4138475
Issued on: 02/06/1979
Inventor: McAinsh ,   et al.

Sustained release pharmaceutical compositions
Patent #: 4248856
Issued on: 02/03/1981
Inventor: Guley ,   et al.

Sustained release pharmaceutical compositions
Patent #: 4248858
Issued on: 02/03/1981
Inventor: Guley ,   et al.

Controlled release formulations of orally-active medicaments
Patent #: 4308251
Issued on: 12/29/1981
Inventor: Dunn ,   et al.

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Inventors

Assignee

Application

No. 827604 filed on 01/29/1992

US Classes:

424/468, Sustained or differential release type424/480, Cellulose or derivative424/494, Cellulose derivatives424/495Ethyl cellulose

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

Foreign Patent References

  • 6203386 AT. 03/13/1987
  • 0066505 EP. 12/13/1982
  • 905000 GB. 09/13/1962

International Class

A61K 009/22

Abstract

A sustained release tablet adapted to provide an initial immediate release of an active agent, a period of no release of the active agent, followed by a substantially constant, rate of release of the active agent. The tablet includes (a) a compressed tablet core containing an active agent, an insoluble binder and an insoluble; (b) a barrier coating formed over the tablet core, the barrier coating including a mixture of soluble and insoluble polymers and a plasticizer; (c) an active coating deposited over the barrier coating, the active coating including an active agent, a soluble polymer and a plasticizer; and (d) a film coating formed over the active coating, the film coating containing a soluble polymer and plasticizer.

Other References

  • Sustained Release Medications, J. C. Johnson, Noyes Data Corporation, Park Ridge, N.J., 1980 pp. 3 and 4
  • Invoice #29944, Jul. 12, 1989, to Thompson Medical Compan
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