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Method of treating inflammatory conditions of the mouth using steroid containing mouthwash which may contain antifungal agents

Patent 5407663 Issued on April 18, 1995. Estimated Expiration Date: Icon_subject April 4, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventor

Application

No. 222277 filed on 04/04/1994

US Classes:

424/49, DENTIFRICES (INCLUDES MOUTH WASH)514/171With additional active ingredient

Examiners

Primary: Mars, Howard T.
Assistant: Cook, Rebecca

Attorney, Agent or Firm

International Classes

A61K 007/28
A01N 045/00

Abstract

Patients may effectively be treated for inflammatory conditions of the mouth using aqueous anti-inflammatory steroids in solutions that can be swished and expectorated as a mouthwash. Such therapy would allow direct contact of the medication with the diseased mucous membranes and would contact areas of the oral cavity that would not usually be reached with application of creams, gels, or ointments. Compositions containing antifungal agents in addition to steroids are particularly useful.Swishing for three to five minutes, then expectorating the aqueous anti-inflammatory-containing, results in maintenance of contact of the active agents with the oral cavity surfaces for a longer time than would application of gels containing those agents. The mode of application is simple and is not repugnant to the patient as is the application of creams, gels, or ointments.

Other References

  • Rothwell et al, Special Care in Dentistry, 1990, pp. 21-25
  • Facts and Comparisons, Adrenal Cortical Steroids, 1984, pp. 119-128b
  • Vademecum Internacional Especiales Farmaceuticas y Biologicas. (1984) Barcelona, pp. 490-58
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