Compositions of gastric acid-resistant microspheres containing buffered bile acids
Patent 5405621 Issued on April 11, 1995. Estimated Expiration Date: 
November 10, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 10, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References Re30910 3004893 Preparation of enteric coated digestive enzyme compositions Process for the production of pancreatin pellets Cylindrical microtablets Patent #: 4828843 InventorAssigneeApplicationNo. 139263 filed on 11/10/1993US Classes:424/490, Coated (e.g., microcapsules)264/7, Coated particles264/13, By extrusion spraying or gravity fall through orifice264/15, SPHEROIDIZING OR ROUNDING OF SOLID PARTICLES424/456, Gelatin424/458, Containing discrete coated particles pellets, granules, or beads424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/474, Coated pills or tablets424/480, Cellulose or derivative424/482, Containing solid synthetic polymers424/494, Cellulose derivatives424/495, Ethyl cellulose424/497, Containing solid synthetic polymers424/715, Carbonate424/717, Bicarbonate427/212, PARTICLES, FLAKES, OR GRANULES COATED OR ENCAPSULATED427/213, Fluidized bed utilized514/867, DIARRHEA514/877, GALLSTONE514/893LIVER DISORDERExaminersPrimary: Webman, Edward J.Foreign Patent References
International ClassesA61K 009/54A61K 009/58 A61K 009/62 A61K 009/16 AbstractDisclosed are gastric acid-resistant polymer-coated buffered-bile acid compositions, process for their preparations and methods of treating digestive disorders, impaired liver function, autoimmune diseases of the liver and biliary tract, preventing colon cancer, cholestasis associated with cystic fibrosis, dissolving gallstones and regulating dietary cholesterol absorption by administering said compositions to a mammal in need of such treatment.Field of SearchCoated (e.g., microcapsules)Containing polysaccharide (e.g., cellulose sugars, etc.) Containing solid synthetic polymers Discrete particles in supporting matrix Where particles are granulated Cellulose or derivative Containing solid synthetic polymers Cellulose derivatives Containing solid synthetic polymers Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof Carbonate Bicarbonate ANTACID, ORAL CIRRHOSIS DIARRHEA GALLSTONE LIVER DISORDER | |
