Use of carrageenans in topical ophthalmic compositions

Patent 5403841 Issued on April 4, 1995. Estimated Expiration Date:

August 18, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

Ocular drug delivery device
Patent #: 4014335
Issued on: 03/29/1977
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Inventors

Assignee

Alcon Laboratories, Inc.

Application

No. 108824 filed on 08/18/1993

US Classes:

514/226.8, 1,3-Thiazines514/54, Polysaccharide514/392, Divalent chalcogen or acyclic nitrogen double bonded at 2-position, or tautomeric equivalent514/912OPHTHALMIC

Examiners

Primary: Fay, Zohreh

Attorney, Agent or Firm

Cheng; Julie J. L.

International Classes

A61K 031/54
A61K 031/415
A61K 031/715

Abstract

Topical ophthalmic compositions of carrageenans which are administrable as a drop but which become more viscous or gel upon instillation in the eye are disclosed. Methods for use of the compositions as topical ophthalmic vehicles for pharmaceutically active agents, and alone as lubricants or tear supplements, are also disclosed.

Other References

Glicksman, M., Gum Technology in the Food Industry, New York: Academic Press, 1969, pp. 218-219
Harris, P. (ed.), Food Gels, New York: Elsevier Applied Science, 1990, Ch. 3 (pp. 79-119) and Ch. 6 (pp. 201-232)
Hawley, G., The Condensed Chemical Dictionary, 10th ed., Van Nostrand Reinhold Co., 1981, p. 202
Stancioff, D., "Reflections in the Interrelationships Beteen Red Seaweed Source chemistry and Uses," Xth Int. Seaweed Symp. (ed. T. Levring), New York: Walter de Gruyter & Co., 1981, pp. 113-212
Stancioff, D. et al., "Infrared and Chemical Studies on Algal Polysaccharides," Proc. VIth Int. Seaweed Symp. (ed. R. Margalef), sy Madrid: Subsecretaria de la Marina Mercante, 1969, pp. 595-60