Patent ReferencesLong acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin Drug units and methods for using same Large intestinal dissociative hard capsules Patent #: 5283064 InventorsApplicationNo. 107744 filed on 08/20/1993US Classes:424/458, Containing discrete coated particles pellets, granules, or beads424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/463Coated capsulesExaminersPrimary: Page, Thurman K.Assistant: Hulina, Amy Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/58Foreign Application Priority Data1991-02-22 GBAbstractAn orally administrable pharmaceutical dosage form for selectively administering a drug to the intestine comprises a plurality of enteric coated granules of the drug contained in an enterically coated capsule which releases the granules in the small intestine. The granules are preferably coated with a coating which remains intact until the coated granules reach at least the ileum and thereafter provide a sustained release of the drug in the colon. Suitable coating materials are selected from the Eudragit range of (meth)acrylate and (meth)acrylic and polymers. The invention has particular application to topically active drugs such as topically active steroids, bismuth salts and complexes, and especially, 5-amino-salicylic acid.Other References
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