U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sustained release preparations

Patent 5399357 Issued on March 21, 1995. Estimated Expiration Date: Icon_subject March 21, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3857933

Pharmaceutical composition of cyclandelate having a high degree of bioavailability
Patent #: 4751241
Issued on: 06/14/1988
Inventor: Motoyama ,   et al.

Controlled-release dosage form comprising acetaminophen, pseudoephedrine and dexbrompheniramine
Patent #: 4777050
Issued on: 10/11/1988
Inventor: Vadino

Erodible matrix for sustained release bioactive composition
Patent #: 4806337
Issued on: 02/21/1989
Inventor: Snipes ,   et al.

Pharmaceutical composition comprising analgesic and anti-inflammatory agent
Patent #: 4844907
Issued on: 07/04/1989
Inventor: Elger ,   et al.

Oral therapeutic system having systemic action Patent #: 4857336
Issued on: 08/15/1989
Inventor: Khanna ,   et al.

Inventors

Assignee

Application

No. 807630 filed on 12/13/1991

US Classes:

424/457, Sustained or differential release424/458, Containing discrete coated particles pellets, granules, or beads424/459, Organic coatings424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/470, Where particles are granulated424/486, Synthetic polymer424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/495, Ethyl cellulose424/497, Containing solid synthetic polymers424/501, Contains solid synthetic resin514/785, Carboxylic acid ester514/951, POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZE514/963, Microcapsule-sustained or differential release514/965Discrete particles in supporting matrix

Examiners

Primary: Webman, Edward J.

Attorney, Agent or Firm

Foreign Patent References

  • 0208144 EP. 06/13/1986
  • 3224619 DE. 05/13/1983
  • 58-13508 JP. 01/13/1983

International Classes

A61K 009/16
A61K 009/26
A61K 009/50
A61K 047/34

Foreign Application Priority Data

1988-11-08 JP

Abstract

There is provided a matrix preparation produced by dispersing a pharmaceutically active ingredient into a matrix which is solid at ambient temperature and comprised of a fatty acid ester of a polyglycerol. The preparation has stable release controlling ability, can be processed to fine granules, granules, capsules, tablets etc., and contributes to reduction of the administration times of the active ingredient and side effects of the ingredient.

Other References

  • Patent Abstract of Japan, vol. 8, No. 145, Jul. 6, 1984
  • "Physical and Chemical Properties of Calcuim Phospates For Solid State Pharmaceutical Formulations", Carstensen et al., Drug Development & Industrial Pharmacy. 16(7), 1121-1133, 1990
  • M. R. Baichwal et al., "The Indian Journal of Pharmacy", Sustained Release Capsules using Polyglycerol Esters, vol. 35, No. 5, Sep.-Oct. 1973, pp. 146-15
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