Controlled release succinic acid microcapsules coated with aqueous acrylics
Patent 5395628 Issued on March 7, 1995. Estimated Expiration Date: 
April 13, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 13, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDipyridamole-containing pharmaceutical form Aqueous coating dispersions Sustained absorption pharmaceutical composition Controlled release powder and process for its preparation Patent #: 4940588 InventorsAssigneeApplicationNo. 870195 filed on 04/13/1992US Classes:424/490, Coated (e.g., microcapsules)424/468, Sustained or differential release type424/474, Coated pills or tablets424/487Acrylic acid and derivativesExaminersPrimary: Page, Thurman K.Assistant: Levy, Neil S. Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/50Foreign Application Priority Data1989-12-28 JPAbstractA controlled release pharmaceutical preparation comprising (a) a core containing a pharmaceutically active substance and an organic acid, and (b) a coating film formed on the surface of the core by aqueous coating of a water-insoluble and water-slightly permeable acrylic polymer containing a trimethylammonium-ethyl group, which exhibits well controlled dissolution and release of the pharmaceutically active substance when administered and can maintain the desired blood level of the active substance for a long period of time, and a method for producing the preparation.Other References
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