Multilayered controlled release pharmaceutical dosage form
Patent 5395626 Issued on March 7, 1995. Estimated Expiration Date: 
March 23, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 23, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPharmaceutical product in the form of a pellet with continuous, delayed medicament substance emission Controlled absorption pharmaceutical formulation Galenic formulations for oral use of rhein derivatives with delayed release for therapeutical use Controlled absorption diltiazem formulation Multi-layer granule Patent #: 4994279 InventorsAssigneeApplicationNo. 217331 filed on 03/23/1994US Classes:424/472, Layered unitary dosage forms424/456, Gelatin424/458, Containing discrete coated particles pellets, granules, or beads424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/495, Ethyl cellulose424/497Containing solid synthetic polymersExaminersPrimary: Page, Thurman K.Assistant: Hulina, Amy International ClassesA61K 009/54A61K 009/62 AbstractThis invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core containing a drug active whereby the drug containing core and at least one other layer of drug active is overcoated with a controlled release barrier layer and preferably an outer layer of additional drug is adapted for immediate release to preferably provide one immediate releasing layer and at least two controlled releasing layers of a water soluble drug from the multilayered coated particle. | |
