"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
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AbstractAn aerosol delivery article provides delivery of aerosol particles of relatively small size without the necessity of exposing the material which is aerosolized to a significant degree of heat or high temperatures. An aerosol forming material is a multi-component material comprising an active ingredient and another ingredient having a relatively low vaporization temperature, and preferably that aerosol forming material is in the form of an emulsion. The aerosol forming material is nebulized so as to provide first stage multi-component aerosol particles of fairly large size. The first stage aerosol particles then are subjected to heat so as to vaporize the other ingredient of that aerosol and cause further dispersion of that first stage aerosol. As such, a second stage aerosol composed of fine particles of active ingredient is provided. The heat used to cause the further dispersion of the first stage aerosol is less than that sufficient to cause vaporization, thermal decomposition or undesirable chemical alteration of the active ingredient.Other References
| InventorApplicationNo. 099015 filed on 07/29/1993US Classes:128/203.17, Electrically heated means producing water vapor128/200.16, Ultrasonic128/203.26Means for heating treating agent, respiratory gas, or mixture thereofField of Search128/200.14, LIQUID MEDICAMENT ATOMIZER OR SPRAYER128/200.15, With tongue depressor128/200.16, Ultrasonic128/200.17, Rotating128/200.18, Spray impinged against baffle in or adjacent flow conduit128/200.19, Means for selectively dispensing different fluids128/200.21, Gas stream aspirating medicament from reservoir128/200.22, Gas flow induced by expansion chamber device (e.g., piston/cylinder ram, squeeze bulb, etc.)128/200.23Pre-pressurized container holding medicamentExaminersPrimary: Burr, Edgar S.Assistant: Raciti, Eric P. US Patent References1771366, 1968509, 2030075, 2057353, 2248591, 2332799, 2764154, 3297029, 3820540, 3859398, 3864544, 3990441, Nebulizer heaterIssued on: 11/09/1976 Inventor: Hoyt , et al.4036224, Portable conditioned air breathing pipe Issued on: 07/19/1977 Inventor: Choporis , et al.4190046, Nebulizer cap system having heating means Issued on: 02/26/1980 Inventor: Virag4214146, Electrically heated vaporizer device for dispensing a thermally volatilizable substance Issued on: 07/22/1980 Inventor: Schimanski4303083, Device for evaporation and inhalation of volatile compounds and medications Issued on: 12/01/1981 Inventor: Burruss, Jr.4523589, Method and apparatus for treating ailments Issued on: 06/18/1985 Inventor: Krauser4655229, Flavor delivery system Issued on: 04/07/1987 Inventor: Sensabaugh, Jr. , et al.4655959, Preparation of non-flammable aerosol propellant microemulsion system Issued on: 04/07/1987 Inventor: Stopper4715387, Aerosol for use in the reduction of tobacco smoking Issued on: 12/29/1987 Inventor: Rose4735217, Dosing device to provide vaporized medicament to the lungs as a fine aerosol Issued on: 04/05/1988 Inventor: Gerth , et al.4765347, Aerosol flavor delivery system Issued on: 08/23/1988 Inventor: Sensabaugh, Jr. , et al.4832012, Intermittent signal actuated nebulizer Issued on: 05/23/1989 Inventor: Raabe , et al.4922901, Drug delivery articles utilizing electrical energy Issued on: 05/08/1990 Inventor: Brooks, et al.4941482, Apparatus for measuring the density of a tobacco stream Issued on: 07/17/1990 Inventor: Heitmann, et al.4951659, Nebulizer with cooperating disengageable on-line heater Issued on: 08/28/1990 Inventor: Weiler, et al.4963367, Drug delivery compositions and methods Issued on: 10/16/1990 Inventor: Ecanow5145604Aqueous emulsion and aerosol delivery system using same Issued on: 09/08/1992 Inventor: Neumiller International ClassesA61M 015/00203.16 203.17 203.26 |