U.S. patents available from 1976 to present.
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Anticonvulsant sorbopyranose sulfamates

Patent 5384327 Issued on January 24, 1995. Estimated Expiration Date: Icon_subject December 22, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Application

No. 994735 filed on 12/22/1992

US Classes:

514/456, Bicyclo ring system having the hetero ring as one of the cyclos (e.g., chromones, etc.)549/396Bicyclo ring system having the hetero ring as one of the cyclos

Examiners

Primary: Chan, Nicky

Attorney, Agent or Firm

International Classes

A61K 031/35
C07D 311/94

Abstract

Sulfamate derivatives having the following formula (I): ##STR1## wherein R1, R2, R3, R4, R5, and R6 are as herein defined, have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, the present invention encompasses pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and novel intermediates are disclosed.

Other References

  • Maryanoff et al., J. Med. Chem., 30(5), 880-7 (1987
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