U.S. patents available from 1976 to present.
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Platelet activating factor antagonists

Patent 5382670 Issued on January 17, 1995. Estimated Expiration Date: Icon_subject July 7, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Platelet activating antagonists Patent #: 5120749
Issued on: 06/09/1992
Inventor: Summers, et al.

Inventors

Application

No. 084257 filed on 07/07/1993

US Classes:

514/339, Ring nitrogen in the polycyclo ring system546/277.4, Bicyclo ring system which is indole (including hydrogenated)546/277.7, Chalcogen attached directly to the five-membered hetero ring by nonionic bonding546/278.1Having -C(=X)-, wherein X is chalcogen, bonded directly to the five- membered hetero ring

Examiners

Primary: Ivy, C. Warren
Assistant: Mach, D. Margaret M.

Attorney, Agent or Firm

International Classes

C07D 213/04
C07D 209/04
C07D 277/04

Abstract

Indole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.

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