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US Patent 5382670 - Platelet activating factor antagonists
US Patent Issued on January 17, 1995
Estimated Patent Expiration Date:
July 7, 2013Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
July 7, 2013Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractIndole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation. | Inventors
ApplicationNo. 084257 filed on 07/07/1993US Classes:514/339, Ring nitrogen in the polycyclo ring system546/277.4, Bicyclo ring system which is indole (including hydrogenated)546/277.7, Chalcogen attached directly to the five-membered hetero ring by nonionic bonding546/278.1Having -C(=X)-, wherein X is chalcogen, bonded directly to the five- membered hetero ringField of Search514/339Ring nitrogen in the polycyclo ring systemExaminersPrimary: Ivy, C. WarrenAssistant: Mach, D. Margaret M. Attorney, Agent or FirmUS Patent References5120749Platelet activating antagonistsIssued on: 06/09/1992 Inventor: Summers, et al. International ClassesC07D 213/04C07D 209/04 C07D 277/04 |
