Patent ReferencesPlatelet activating antagonists Patent #: 5120749 Inventors
ApplicationNo. 084257 filed on 07/07/1993US Classes:514/339, Ring nitrogen in the polycyclo ring system546/277.4, Bicyclo ring system which is indole (including hydrogenated)546/277.7, Chalcogen attached directly to the five-membered hetero ring by nonionic bonding546/278.1Having -C(=X)-, wherein X is chalcogen, bonded directly to the five- membered hetero ringExaminersPrimary: Ivy, C. WarrenAssistant: Mach, D. Margaret M. Attorney, Agent or FirmInternational ClassesC07D 213/04C07D 209/04 C07D 277/04 AbstractIndole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.Field of SearchRing nitrogen in the polycyclo ring system |
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