Low steroid dose dry pharmaceutical preparation
Patent 5382434 Issued on January 17, 1995. Estimated Expiration Date: 
March 22, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 22, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3423507 3568828 3626063 3671633 3802914 Method for contraception by the application of combination-type sequential preparations Compositions and method of treating with stereoisomeric mixtures of 2-unsymmetrical 16,17-methylenedioxy steroids Method of contraception Triphasic oral contraceptive Spray-dried lactose formulation of micronized glyburide InventorsAssigneeApplicationNo. 216236 filed on 03/22/1994US Classes:424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/464, Tablets, lozenges, or pills514/169, Cyclopentanohydrophenanthrene ring system DOAI514/171, With additional active ingredient514/174, -O-C-O- is part of a hetero ring (e.g., acetonide, etc.)514/175, -C(=O)-O-is part of a hetero ring (e.g., lactone, etc.)514/960SIGNIFICANT, TABLET FORMULATION (E.G., DESIGNATED EXCIPIENT, DISINTEGRANT, GLYDENT OR LUBRICANT, ETC.)ExaminersPrimary: Cintins, Marianne M.Assistant: Criares, T. J. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/20A61K 031/56 A61K 031/585 Foreign Application Priority Data1991-03-12 EPAbstractDisclosed are dry pharmaceutical preparations containing potent steroidal medicinal agents in combination with an excipient capable of binding the agent to an extent greater than 80% and a having a demixing potential of less than 10% for said agent. Such excipients include spray-dried polyalcohols, granulated -lactose monohydrate, or mixtures thereof. Also disclosed is a process of manufacturing stable tablets containing nearly identical amounts of at least one steroidal medicinal agent present in each tablet in an amount varying from 0.005 to 0.5 percent by weight of the tablet. Also disclosed is a dry mix consisting essentially of 1 to 100 parts, by weight, of at least one medicinal agent uniformly distributed throughout 2000 to 20,000 parts, by weight, of the described excipients. The mixture can be used to make dry dosage forms such as capsules, tablets, powders, and slugged granulates.Other References
Field of SearchTablets, lozenges, or pillsWith claimed perfecting feature in contents (e.g., excipient, lubricant, etc.) With additional active ingredient -O-C-O- is part of a hetero ring (e.g., acetonide, etc.) SIGNIFICANT, TABLET FORMULATION (E.G., DESIGNATED EXCIPIENT, DISINTEGRANT, GLYDENT OR LUBRICANT, ETC.) | |
