Patent 5380831 Issued on January 10, 1995. Estimated Expiration Date: May 3, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
536/23.71, Bacillus thuringiensis insect toxin435/69.1, Recombinant DNA technique included in method of making a protein or polypeptide435/91.1, Polynucleotide (e.g., nucleic acid, oligonucleotide, etc.)435/91.5, Acellular preparation of polynucleotide435/91.52Involving a ligase (6.)
Synthetic Bacillus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
Other References
Taylor et al (1987) Mol. Gen. Genet. 210:572-577
Joshi (1987) Nucl. Acids Res. 15:9627-9640
Vankan et al (1988) Embo J. 7:791-799
Tuerk et al (1988) Proc. Natl. Acad. Sci. 85:1364-1368
Brown et al (1986) Embo J. 5:2749-2758
Hofte et al (1989) Microbiological Reviews 53(2):242-255
Fischhoff et al (1987) Bio/Technology 5:807-813
Vasil (Apr. 1988) Biotechnology 6:397-402
Sekar et al (Oct. 1987) Proc. Natl. Acad. Sci. 84:7036-7040
Vaeck et al (1987) Nature 328:33-37
Barton et al (1987) Plant Physiology 85:1103-1109
Holkema et al (1987) Mol. Cell. Biol. 7:2914-2924
Grantham et al (1986) Oxford Surveys in Evol. Biol. 3:48-81
Adang et al. (1987) Molecular Strategies for Crop Protection pp. 345-35
May 3, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
