Methods and compositions for treating allergic disorders and other disorders metabolic derivatives of terfenadine
Patent 5375693 Issued on December 27, 1994. Estimated Expiration Date: 
February 2, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 2, 2014. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPiperidine derivatives Patent #: 4254129 InventorsAssigneeApplicationNo. 191061 filed on 02/02/1994US Classes:514/317Additional ring containingExaminersPrimary: Henley, III, RaymondAssistant: Jarvis, William R. A. Attorney, Agent or FirmForeign Patent References
International ClassA61K 031/445AbstractMethods and compositions are disclosed utilizing metabolic derivatives of terfenadine for the treatment of allergic disorders while avoiding the concomitant liability of adverse effects associated with the terfenadine. The metabolic derivatives of terfenadine are also useful for the treatment of retinopathy and other small vessel disorders associated with diabetes mellitus and such other conditions as may be related to the antihistamine activity of terfenadine. For example, the metabolic derivatives of terfenadine are useful for the treatment of asthma, motion sickness, and vertigo, without the concomitant liability of adverse effects associated with terfenadine. Furthermore, the metabolic derivatives of terfenadine, in combination with non-steroidal anti-inflammatory agents or other nonnarcotic analgesics, or in combination with a decongestant, cough suppressant/antitussive or expectorant, are useful for the treatment of cough, cold, cold-like, and/or flu symptoms and the discomfort, headache, pain, fever, and general malaise associated therewith, without the concomitant liability of adverse effects associated with terfenadine.Other References
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