Method of treating fescue toxicosis with domperidone
Patent 5372818 Issued on December 13, 1994. Estimated Expiration Date: 
February 1, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 1, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds Methods of treating and preventing tall fescue toxicosis by the administration of thiamin Treatment for fescue toxicosis in grazing animals Prevention of fescue toxicosis Patent #: 4880632 InventorsAssigneeApplicationNo. 012296 filed on 02/01/1993US Classes:424/442, Animal food514/276, Thiamines (e.g., vitamin B1, etc.)514/450The hetero ring has at least seven membersExaminersPrimary: Michl, Paul R.Assistant: Benston, William E. Jr. Attorney, Agent or FirmInternational ClassA23K 001/165AbstractA novel method for using domperidone, a dopamine receptor antagonist, for treating fescue toxicosis in animals is provided. Fescue toxicosis is caused by animals grazing on endophyte-infected fescue grass. Treatment of the animal with various dosages of domperidone results in effective management of the toxin. The domperidone treatments do not cause any substantial adverse behavioral or neurological side effects in the animal. Domperidone is a more effective treatment for fescue toxicosis than previously-known agents such a metoclopramide and sulpiride.Other References
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