U.S. patents available from 1976 to present.
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Use of ascorbic acid in the genital area and corresponding medicinal preparations

Patent 5371107 Issued on December 6, 1994. Estimated Expiration Date: Icon_subject December 22, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Pharmaceutical composition for intrarectal administration, and suppository prepared therefrom
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Protective additive to vaginal products and catamenials
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Inventors

Assignee

Application

No. 172641 filed on 12/22/1993

US Classes:

514/474, Ascorbic acid or derivative (e.g., vitamin C, etc.)514/931, VENERAL DISEASE514/934, Virus514/967, VAGINAL514/969OINTMENT OR SALVE BASE

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

Foreign Patent References

  • 0046409 EP. 02/13/1982
  • 527241 EP. 02/13/1993
  • 2646604 FR. 05/13/1989
  • 8704069 WO. 07/13/1987
  • 8804176 WO. 06/13/1988

International Classes

A61K 031/375
A61K 009/06

Abstract

A method of treating conditions of amine vaginitis, purulent vaginitis and dysplasia of the mouth of the uterus resulting from papilloma virus infection in the genital region of female animals by topically applying ascorbic acid to the affected region. The invention also provides a medicinal composition in the form of a an ointment or tablet containing about 3% to about 50% by weight of ascorbic acid and the balance a pharmaceutically acceptable ointment or tabletting carrier.

Other References

  • JP-A-61 65 822, Patent Abstracts of Japan, vol. 10, No. 230, (c-365)[2286]; Aug. 8, 1986, p. 111 C 365
  • Rote Liste, 1987, Editio Cantor, Aulendorf, Germany, No. 45 126 and 45 127
  • S. L. Romney, et al, "Plasma Vitamin C and Uterine Cervical Dysplasia", American Journal of Obstetrics and Gynecology, vol. 151, No. 7, Apr. 1, 1985, pp. 976-980
  • B. Hoffmann, et al, "The Vitamin C Concentrations in the Cervical Mucous in Women Infested and Uninfested by Trichomonas Vaginalis"; Ginekologia Polska, vol. 40, No. 7, 1969, pp. 773 to 77
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