Prolonged-release liquid type of pharmaceutical preparation comprising drug-resin complex and benzoate preservative
Patent 5368852 Issued on November 29, 1994. Estimated Expiration Date: 
March 31, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 31, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProlonged release pharmaceutical preparations Sustained release drug-resin complexes Drug adsorbates Patent #: 5032393 InventorsAssigneeApplicationNo. 041046 filed on 03/31/1993US Classes:424/78.1, Ion exchange resin424/78.12, Adsorbate or treating agent contains nitrogen424/78.13Oxygen or sulfur heterocycleExaminersPrimary: Page, Thurman K.Assistant: Kulkosky, Peter F. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/74A61K 009/08 Foreign Application Priority Data1992-04-03 JPAbstractThe present invention provides a prolonged-release liquid type of pharmaceutical preparation prepared by coating a pharmaceutically active drug-ion exchange resin complex which was treated previously with an impregnating agent, with a water permeable diffusion barrier material, followed by suspending the coated complex in a solution containing preservatives. The formulation of the present invention does not develop the rupture of the diffusion barrier film even in a solution containing preservatives. Therefore the formulation of the present invention is a prolonged-release liquid type of pharmaceutical preparation which is stable and does not lose the controlled release of the active ingredient. | |
