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Retroviral protease inhibiting compounds

Patent 5354866 Issued on October 11, 1994. Estimated Expiration Date: Icon_subject September 14, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Application

No. 121673 filed on 09/14/1993

US Classes:

546/265Having -C(=X)-, wherein X is chalcogen, bonded directly to the acyclic nitrogen

Examiners

Primary: Fan, Jane T.

Attorney, Agent or Firm

Foreign Patent References

  • 393445 EP. 10/24/1990
  • 402646 EP. 12/24/1990
  • 428849 EP. 05/24/1991
  • 441192 EP. 08/24/1991
  • 3829594 DE. 03/24/1990
  • 4003575 DE. 08/24/1991
  • WO88/02374 WO. 04/24/1988

International Class

C07D 401/10

Abstract

A retroviral protease inhibiting compound of the formula A--X--B is disclosed. Also disclosed are a composition and method for inhibiting a retroviral protease and for treating an HIV infection. Also disclosed are processes and intermediates useful for the preparation of the retroviral protease inhibitors.

Other References

  • Zeffren et al. The Study of Enzyme Mechanism p. 87 1974
  • Wade Jr. Organic Chemistry p. 349 198
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