U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method for preparing medicinal aerosol formulation containing coated medicament

Patent 5348730 Issued on September 20, 1994. Estimated Expiration Date: Icon_subject March 17, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3014844

Aerosol propellant compositions
Patent #: 4174295
Issued on: 11/13/1979
Inventor: Bargigia ,   et al.

Aerosol compositions containing finely divided solid materials
Patent #: 4352789
Issued on: 10/05/1982
Inventor: Thiel

Aerosol application of encapsulated materials
Patent #: 4520142
Issued on: 05/28/1985
Inventor: Leinen

Nedocromil calcium and use thereof in treatment of reversible obstructive airways disease
Patent #: 4849427
Issued on: 07/18/1989
Inventor: Nassim ,   et al.

Methods of preparing pro-liposome dispersions and aerosols Patent #: 5141674
Issued on: 08/25/1992
Inventor: Leigh

Inventors

Application

No. 838747 filed on 03/17/1993

US Classes:

424/45, Organic pressurized fluid424/43, EFFERVESCENT OR PRESSURIZED FLUID CONTAINING424/46, Powder or dust containing424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof427/2.14, Particulate or unit-dosage-article base (e.g., tablet, pill, pellet, capsule, liposome, powder, controlled-release implant, suppository; excluding transdermal patch)514/951, POWDERS, GRANULES OR PARTICLES OF SPECIFIED MESH OR PARTICLE SIZE514/975CHARACTERIZED BY THE DESIGNATED SURFACTANT USED

Examiners

Primary: Page, Thurman K.
Assistant: Harrison, Robert H.

Attorney, Agent or Firm

Foreign Patent References

  • 372777A2 EP. 06/13/1990
  • 1719443 DE. 04/13/1972
  • 837465 GB. 06/13/1960
  • 977934 GB. 12/13/1964
  • 1063512 GB. 03/13/1967
  • 2001334 GB. 01/13/1979
  • 90/07333 WP. 01/13/1990

International Classes

A61K 009/12
A61K 009/72

Foreign Application Priority Data

1989-09-20 GB

Abstract

A method for preparing a self-propelling, powder dispersing aerosol composition comprising at least 0.0001% by weight of a finely-divided solid medicament coated with a non-perfluorinated surface active dispersing agent which constitutes at least 0.0001% by weight of the coated solid material, and suspended in an aerosol propellant in which the non-perfluorinated surface-active dispersing agent is substantially insoluble. Propellant-insoluble non-perfluorinated surfactants are used to prepare stable dispersions of powdered medicament by way of pre-coating the medicament with the surfactant prior to admixture with propellant.

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