U.S. patents available from 1976 to present.
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Method and device for treating and enlarging body lumens

Patent 5342348 Issued on August 30, 1994. Estimated Expiration Date: Icon_subject December 4, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Cardiovascular grafts
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Issued on: 11/17/1981
Inventor: Bokros

Percutaneous endovascular stent and method for insertion thereof
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Issued on: 04/08/1986
Inventor: Gianturco

Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
Patent #: 4733665
Issued on: 03/29/1988
Inventor: Palmaz

Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
Patent #: 4739762
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Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
Patent #: 4776337
Issued on: 10/11/1988
Inventor: Palmaz

Endovascular stent and delivery system
Patent #: 4800882
Issued on: 01/31/1989
Inventor: Gianturco

Triaxially-braided fabric prosthesis
Patent #: 4834755
Issued on: 05/30/1989
Inventor: Silvestrini ,   et al.

Surgical stent method and apparatus
Patent #: 4990155
Issued on: 02/05/1991
Inventor: Wilkoff

Radially expandable endoprosthesis and the like
Patent #: 5019090
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Inventor: Pinchuk

Thromboresistant coating
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Issued on: 10/01/1991
Inventor: Pinchuk

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Inventor

Application

No. 985382 filed on 12/04/1992

US Classes:

604/891.1, Implanted dynamic device or system604/28, Method606/198Expanding dilator (e.g., expanding arm, etc.)

Examiners

Primary: Rosenbaum, C. Fred
Assistant: Alexander, Vanitha

Attorney, Agent or Firm

Foreign Patent References

  • 0281482 EP. 09/13/1988
  • 0433011 EP. 06/13/1991
  • 87/04935 WO. 08/13/1987
  • 9117789 WO 11/13/1991
  • 92/11890 WO. 07/13/1992
  • 92/11895 WO. 07/13/1992

International Class

A61K 009/22

Abstract

The present invention relates generally to stents having delivery matrices which provide for the controlled release of bioactive substances. The delivery matrices comprise porous and erodible filaments, and multiple filaments may be employed in order to release different bioactive substances and/or the same bioactive substance at different delivery rates. The stents are particularly useful for preventing restenosis of dilated body lumens, such as blood vessels. Methods for preventing stenosis of dilated body lumens or locally delivering bioactive compounds to tissue are also provided.

Other References

  • Chasin et al. "Polyanhydrides as Drug Delivery Systems" in Biodegradable Polymers . . . , Mercel Dekker 1990 pp. 43-70
  • Langer (1990) Science 249:1527-1532
  • Langer and Moses (1991) J. Cell. Biochem. 45:340-34
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