U.S. patents available from 1976 to present.
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Method for determining blood pressure utilizing a neural network

Patent 5339818 Issued on August 23, 1994. Estimated Expiration Date: Icon_subject September 9, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

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Inventors

Application

No. 119451 filed on 09/09/1993

US Classes:

600/490, Force applied against skin to close blood vessel128/925, Neural network600/493, Electric signal generated by sensing means responsive to pulse or Korotkoff sounds706/924Medical

Examiners

Primary: Cohen, Lee S.
Assistant: Nasser, Robert L.

Attorney, Agent or Firm

International Class

A61B 005/00

Abstract

A method and device for indirect, quantitative estimation of blood pressure attributes and similar variable physiological parameters utilizing indirect techniques. The method of practice includes (i) generating a sequence of signals which are quantitative dependent upon the variable parameter, (ii) transmitting and processing the signals within a computer system and associated neural network capable of generating a single output signal for the combined input signals, (iii) directly determining an actual value for the parameter concurrent with the indirect generation of signals of the previous steps, (iv) applying weighting factors within the neural network at interconnecting nodes to force the output signal of the neural network to match the true value of the parameter as determined invasively, (v) recording the input signals, weighting factors and true value as training data within memory of the computer, and (vi) repeating the previous steps to develop sufficient training data to enable the neural network to accurately estimate parameter value upon future receipt of on-line input signals. Procedures are also described for preclassification of signals and artifact rejection. Following training of the neural network, further direct measurement is unnecessary and the system is ready for diagnostic application and noninvasive estimation of parameter values.

Other References

  • "Natural Underwater Sounds Identification by Use of Neural Networks and Linear Techniques," Legitimus et al. Jul. 1990
  • "An Introduction to Computing with Neural Nets", Lippman, Richard P. IEEE ASSP MAGAZINE, (Apr. 1978) pp. 4 through 22
  • "Neural Computers" Stubs, Derek F. M. D. Computing. vol. 5: (3) pp. 1-12, 1988
  • "Use of Neural Networks for Detection of Artifiacts in Arterial Pressure Waveforms", Anthony V. Sebald PH.D
  • "Heart Sound Analysis Using Neural and Statistical Classifiers; A Comparison", Barschdorff, Dieter, Bothe, Achim, Rengshausen, Ute
  • "Training Neural Networks for ECG Feature Recognition" K. Zhu, P. D. Noakes and A. D. P. Green
  • "New Methods for ECG Classification-A Comparative Study" D. Edelstein, M. Fleslsher, G. F. Inba
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