U.S. patents available from 1976 to present.
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Composition comprising a tramadol material and acetaminophen and its use

Patent 5336691 Issued on August 9, 1994. Estimated Expiration Date: Icon_subject November 10, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3652589

Inventors

Application

No. 974865 filed on 11/10/1992

US Classes:

514/629, R is hydrogen or a lower saturated alkyl of less than seven carbons514/646Benzene ring containing

Examiners

Primary: Waddell, Frederick E.
Assistant: Jarvis, William R. A.

Attorney, Agent or Firm

International Class

A61K 031/165

Abstract

This invention relates to a composition comprising a tramadol material and acetaminophen, and its use. As used herein tramadol refers to various forms of tramadol. The compositions are pharmacologically useful in treating pain and tussive conditions. The compositions are also subject to less opioid side-effects such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (synergistic).

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