Nitrofurantoin crystals
Patent 5332832 Issued on July 26, 1994. Estimated Expiration Date: 
August 11, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 11, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesInventorsAssigneeApplicationNo. 928140 filed on 08/11/1992US Classes:548/316.1Plural acyclic chalcogens bonded directly at the 2- and at the 4- or 5- positions of the 1,3-diazole ring [e.g., N-(5-nitro-2-furfuryliden)-1- amino-hydantoin, etc.]ExaminersPrimary: Higel, Floyd D.Attorney, Agent or FirmForeign Patent References
International ClassesC07D 233/40A61K 009/52 A61K 031/415 AbstractNitrofurantoin particulates comprising discrete particulates of nitrofurantoin wherein:(a) said particulates are larger than about 200 mesh size; and(b) the BET surface area of said particulates is at least about 0.2 M2 /g.Preferably, the surface of said particulates consists essentially of nitrofurantoin monohydrate. Also preferably, said particulates comprise at least about 5%, more preferably at least about 50% of nitrofurantoin monohydrate. Preferred compositions of this invention comprise these nitrofurantoin particulates in an aqueous suspension. The nitrofurantoin particulates of this invention are highly efficacious for the delivery of nitrofurantoin in oral dosage forms.Other References
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