Patent ReferencesElement for analysis of liquids Element, structure and method for the analysis or transport of liquids Automated apparatus for photometrically detecting immunological agglutinating reactions Multilayer element for analysis Method for correction of calibration curve in dry analytical process Multilayer analysis element Method for quantitative analysis of analyte in liquid sample using analytical element Analyzer having humidity control apparatus Analytical assay method Patent #: 5166079 InventorsApplicationNo. 962461 filed on 10/16/1992US Classes:436/518, INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS356/243.2, For fluid suspended particles422/56, Having reagent in absorbent or bibulous substrate422/57, Having coated reagent422/82.05, Measuring optical property by using ultraviolet, infrared, or visible light435/3, CONDITION RESPONSIVE CONTROL PROCESS435/967, STANDARDS, CONTROLS, MATERIALS (E.G., VALIDATION STUDIES, BUFFER SYSTEMS, ETC.)436/169, With reagent in absorbent or bibulous substrate436/170, Plural superposed layers436/528, Carrier is organic436/805OPTICAL PROPERTYExaminersPrimary: Scheiner, Toni R.Assistant: Chin, Christopher L. Attorney, Agent or FirmForeign Patent References
International ClassesG01N 033/543G01N 033/558 AbstractA method for determining the amount of an analyte in a sample fluid utilizing an assay element which comprises at least one reagent layer. The assay method includes the steps of optically reading a signal producing species, e.g., a fluorescent label, a first time prior to depositing the sample fluid on the assay element and a second time, at the same wavelength and in the same location within the assay element after the sample fluid has been applied to the assay element and the sample analyte has interacted with the reagent(s) present in the assay element. The first, or dry, reading is corrected for relative humidity and/or temperature variations.Field of SearchHaving reagent in absorbent or bibulous substrateHaving coated reagent In holder or container having special form With specific analytical program control means Sample mechanical transport means in or for automated analytical system Measuring optical property by using ultraviolet, infrared, or visible light CONDITION RESPONSIVE CONTROL PROCESS OPTICAL SENSING APPARATUS PREVENTION OR REMOVAL OF INTERFERING MATERIALS OR REACTANTS OR OTHER TREATMENT TO ENHANCE RESULTS (E.G., DETERMINING OR PREVENTING NONSPECIFIC BINDING, ETC.) STANDARDS, CONTROLS, MATERIALS (E.G., VALIDATION STUDIES, BUFFER SYSTEMS, ETC.) With reagent in absorbent or bibulous substrate Plural superposed layers INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS Carrier is organic OPTICAL PROPERTY |
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