U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Antimicrobial compositions useful for medical applications

Patent 5326567 Issued on July 5, 1994. Estimated Expiration Date: Icon_subject June 28, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3006870

3092552

3531433

3639575

3645950

Oligodynamic catheter
Patent #: 4054139
Issued on: 10/18/1977
Inventor: Crossley

Antibacterial and antifungal material
Patent #: 4181786
Issued on: 01/01/1980
Inventor: Mune ,   et al.

Anti-fungal and anti-bacterial polyurethanes
Patent #: 4263424
Issued on: 04/21/1981
Inventor: Buckley ,   et al.

Silver ion gel compositions
Patent #: 4376764
Issued on: 03/15/1983
Inventor: Schmolka

Pharmaceutical formulations
Patent #: 4451447
Issued on: 05/29/1984
Inventor: Kaplan ,   et al.

More ...

Inventor

Application

No. 082168 filed on 06/28/1993

US Classes:

424/405, Biocides; animal or insect repellents or attractants (e.g., disinfectants, pesticides, etc.)424/78.07, Anti-infective424/78.08, SOLID SYNTHETIC ORGANIC POLYMER AS DESIGNATED ORGANIC ACTIVE INGREDIENT (DOAI)424/447, Bandages with incorporated medicaments424/618, Silver424/669, Iodide424/677, Alkali or alkaline earth chloride (e.g., barium or lithium chloride, etc.)424/680, Sodium chloride424/723Elemental bromine or bromine compound containing

Examiners

Primary: Page, Thurman K.
Assistant: Hulina, Amy

Attorney, Agent or Firm

Foreign Patent References

  • 3523023 DE. 01/12/1987

International Classes

A01N 025/00
A01N 059/08
A61L 015/16
A61K 033/14

Abstract

Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess halide anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices and adhesives to impart infection-resistance.

Other References

  • Weber et al. "Spherical Wrapping of a Linear Polyether around a Cation . . . ", Angew. Chem. Int. Ed. Engl. 18(3): 226-227 (1979)
  • Weber et al. "S-Shaped Binuclear Cation Complex of a Linear Polyether . . . ", Angew. Chem. Int. Ed. Engl. l18(3): 227-228 (1979)
  • Thomas et al. "Metal Ion Complexation of Poly(ether)urethanes"; 131-145
  • Hamon et al. "The Caton-Chelation Mechanism of Metal-ion Sorption By Polyurethane" Talanta 29: 313-326 (1982)
  • Iwamoto et al. "Structure of Poly(ethylene Oxide) Complexes . . . ", J. Polymer Sci., 6(A2): 1509-1525 (1968)
  • Sotobayashi "Liquid-Liquid Extraction of Cobalt(II) With Polyethyleneglycol . . . ", Chem. Ltrs., 77-80 (1976)
  • Sotobayashi "Liquid-Liquid Extraction of Various Metal Ions With Polyethyleneglycol . . . ", Chem. Ltrs. 585-588 (1976)
  • Yanagida et al. "Metal-Ion Complexation of Noncyclic Poly(oxyethylene) Derivatives, I. Solvent Extraction . . . ", Soc. Bulletin Chem., Japan, 50(6): 1386-1390 (1977)
  • Yanigida et al. "Metal-ion Complexation of Noncyclic Poly(oxyethylene) Derivatives, II. PMR Studies . . . ", Soc. Bulletin, Chem., Japan, 51(5): 1294-1299 (1978)
  • Sotobayashi "Liquid-Liquid Extraction of Some Actinides with Polyethyleneglycol & Derivatives", J. Radioanalytical Chem., 36: 145-152 (1977)
  • Saenger et al. "Wrapping of Metal Cations by Linear Polyethers", Israel J. of Chem., 18: 253-258 (1979)
  • Kolthoff "Application of Macrocyclic Compounds in Chemical Analysis", Analytical Chem. 51(5): 1R-22 R
  • Frensdorff "Salt Complexes of Cyclic Polyethers . . . ", J. Am. Chem. Society, 93(19): (1971)
  • Pedersen "Cyclic Polyethers and Their Complexes with Metal Salts", J. Am. Chem. Society, 89: 26 (1967)
  • Paik Sung et al. "ESCA Studies or Surface Chemical Composition of Segmented Polyurethanes", J. Biomed. Mat. Research, 13: 161-171 (1979)
  • Chow et al. "The Extraction and Determination of Thiocyanate Complexes by Use of Polyurehtane Foam", Talanta, 30(8) 620-622 (1983
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?