U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Iontophoretic structure for medical devices

Patent 5322520 Issued on June 21, 1994. Estimated Expiration Date: Icon_subject November 12, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method of using electrodes having antiseptic properties for LIDC therapy
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Method of in vivo sterilization of surgical implantables
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Iontophoretic catheter device
Patent #: 4411648
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Inventor: Davis ,   et al.

Iontophoresis device
Patent #: 4474570
Issued on: 10/02/1984
Inventor: Ariura ,   et al.

Antimicrobial surgical implants
Patent #: 4476590
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Catheter
Patent #: 4483688
Issued on: 11/20/1984
Inventor: Akiyama

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Inventor

Assignee

Application

No. 975597 filed on 11/12/1992

US Classes:

604/265, With body soluble, antibactericidal or lubricating materials on conduit604/20, Infrared, visible light, ultraviolet, X-ray or electrical energy applied to body (e.g., iontophoresis, etc.)604/21With tubular injection means inserted into body

Examiners

Primary: Yasko, John D.
Assistant: Alexander, Vanitha

Attorney, Agent or Firm

Foreign Patent References

  • 0206024 EP 12/12/1986
  • 9116946 EP. 11/12/1991
  • 3830359 DE. 12/12/1989
  • 1582016 GB. 12/12/1980

International Class

A61M 005/32

Abstract

An iontophoretic structure for medical devices is provided that uses controlled electrical current derived from two dissimilar galvanic materials to drive oligodynamic metal ions into solution to kill bacteria on and near the device to which the structure is affixed. In one embodiment, a first galvanic material separated from a second galvanic material by a resistive material produces an anti-bacterial current flow when placed in contact with an electrolytic fluid. In another embodiment, a cylindrical elastomeric catheter incorporates a first and a second galvanic material separated by a resistive material which controls a current flow between the galvanic materials when the catheter is immersed in an electrolytic fluid. The galvanic materials can be dissimilar metal powders embedded in a conductive polymer substrate that forms an iontophoretic composite material, or dissimilar metals arranged in layers separated by a resistive layer. In yet another embodiment, the iontophoretic composite material is configured as an infection control sleeve that covers a portion of an ordinary catheter or cannula. Methods of protecting implantable medical devices and body structures with the iontophoretic structures are also provided.

Other References

  • J. A. Spadaro et al., Antibacterial Effects of Silver Electrodes with Weak Direct Current, Antimicrobial Agents and Chemotherapy, vol. 6, No. 5, Nov., 1974, pp. 637-642
  • C. P. Davis et al., Electrode and Bacterial Survival With Iontophoresis In Synthetic Urine, The Journal of Urology, vol. 147, May, 1992, pp. 1310-131
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