Assays and kits incorporating nucleic acid probes containing improved molecular switch
Patent 5312728 Issued on May 17, 1994. Estimated Expiration Date: 
May 4, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 4, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMicrobial hybrid promoters Process for amplifying nucleic acid sequences Transcription terminators Assay, reagent and kit employing nucleic acid strand displacement and restriction endonuclease cleavage Patent #: 4725537 Inventors
AssigneeApplicationNo. 878230 filed on 05/04/1992US Classes:435/6, Involving nucleic acid435/91.1Polynucleotide (e.g., nucleic acid, oligonucleotide, etc.)ExaminersPrimary: Zitomer, Stephanie W.Attorney, Agent or FirmForeign Patent References
International ClassesC12Q 001/68C12P 019/34 AbstractA probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.Other References
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