U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Delivery devices with pulsatile effect

Patent 5308348 Issued on May 3, 1994. Estimated Expiration Date: Icon_subject May 5, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3760806

Sustained release capsule for ruminants
Patent #: 4416659
Issued on: 11/22/1983
Inventor: Simpson ,   et al.

Medical capsule device
Patent #: 4507115
Issued on: 03/26/1985
Inventor: Kambara ,   et al.

Release device
Patent #: 4642230
Issued on: 02/10/1987
Inventor: Whitehead ,   et al.

Pulsatile drug delivery system
Patent #: 4723958
Issued on: 02/09/1988
Inventor: Pope ,   et al.

Constant release system with pulsed release
Patent #: 4777049
Issued on: 10/11/1988
Inventor: Magruder ,   et al.

Pulsed drug delivery of doxylamine
Patent #: 4842867
Issued on: 06/27/1989
Inventor: Ayer ,   et al.

Heavy density depot
Patent #: 4867980
Issued on: 09/19/1989
Inventor: Edwards ,   et al.

Multi-layer delivery system
Patent #: 4874388
Issued on: 10/17/1989
Inventor: Wong, et al.

Multi-layer delivery system
Patent #: 4957494
Issued on: 09/18/1990
Inventor: Wong, et al.

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Inventors

Application

No. 058151 filed on 05/05/1993

US Classes:

604/892.1, Osmotic or diffusion pumped device or system424/422, Implant or insert604/143, Piston impelled by gas or vacuum pressure604/890.1CONTROLLED RELEASE THERAPEUTIC DEVICE OR SYSTEM

Examiners

Primary: Rosenbaum, C. Fred
Assistant: Smith, Chalin

Attorney, Agent or Firm

Foreign Patent References

  • WO8600519 GB 01/13/1986

International Class

A61K 009/22

Abstract

Delivery devices which include a beneficial agent and an activating mechanism in separate compartments separated by a moveable partition are designed to deliver the beneficial agent in a pulsatile manner through an orifice. The pulsatile delivery is achieved by a band of resilient material which is placed over the orifice. The resilient material is sufficiently tight to substantially seal the orifice when the pressure within the device is below a threshold level while at the same time being capable of being stretched when the internal pressure exceeds the threshold.

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