Patent ReferencesIntravascularly administrable, magnetically responsive nanosphere or nanoparticle, a process for the production thereof, and the use thereof Drug delivery system Viral decoy vaccine Patent #: 5178882 InventorsApplicationNo. 029773 filed on 03/11/1993US Classes:424/493, Containing polysaccharides (e.g., sugars)424/418, Protein or derivative or polysaccharide or derivative424/490, Coated (e.g., microcapsules)424/491, Containing proteins and derivatives424/494, Cellulose derivatives424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof424/499, Contains proteins or derivative or polysaccharides or derivative514/814, ANEMIA514/832, BLOOD SUBSTITUTE514/833BLOOD PLASMA EXTENDERExaminersPrimary: Page, Thurman K.Assistant: Spear, James M. Attorney, Agent or FirmInternational ClassA61K 009/14AbstractA red blood cell surrogate which is composed of a nanocrystalline core particle to which an oxygen carrier such as hemoglobin is bound. An oxygen carrier anchor coating is provided between the nanocrystalline core particle and the oxygen carrier in order to provide binding of the oxygen carrier to the nanocrystalline core particle without denaturing the oxygen carrier or otherwise destroying its oxygen carrying capacity. The nanocrystalline core particle with the oxygen carrier bound thereto is coated with an exterior layer of lipid.Other References
Field of SearchContaining polysaccharides (e.g., sugars)Cellulose derivatives Contains proteins or derivative or polysaccharides or derivative Coated (e.g., microcapsules) Protein or derivative or polysaccharide or derivative Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof Containing proteins and derivatives ANEMIA BLOOD SUBSTITUTE BLOOD PLASMA EXTENDER | |