Pharmaceutical composition for rapid suspension in water
Patent 5306506 Issued on April 26, 1994. Estimated Expiration Date: 
March 3, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 3, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesTherapeutic compositions Pharamaceutical preparations in the form of instant granules or tablets and process for their manufacture Patent #: 4888177 InventorsAssigneeApplicationNo. 838818 filed on 03/03/1992US Classes:424/466, Effervescent424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/493, Containing polysaccharides (e.g., sugars)424/494, Cellulose derivatives514/777, Carbohydrate or lignin, or derivative514/778, Starch or derivative514/779, Algin or derivative514/781, Cellulose or derivative514/782, Natural gum or resin514/784Carboxylic acid or salt thereofExaminersPrimary: Page, Thurman K.Assistant: Spear, James M. Attorney, Agent or FirmInternational ClassA61K 009/46Foreign Application Priority Data1990-07-11 ITAbstractThe invention provides a solid pharmaceutical composition for addition to water to produce a suspension of a drug comprising (a) a drug which is substantially water-insoluble or microencapsulated; (b) a thickening or suspending agent; (c) a pharmaceutically acceptable acid; (d) a pharmaceutically acceptable carbonate or bicarbonate; characterised in that the weight ratio of c+d:b is from 1:1.5 to 1:15 and the amount of c+d is sufficient to obtain rapid hydration of the thickening or suspending agent (b) when the composition is mixed with water such that a homogeneous suspension of the drug is obtained within 30 seconds. A method for preparing the composition is also described. | |
