U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts

Patent 5300300 Issued on April 5, 1994. Estimated Expiration Date: Icon_subject April 1, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Gastric juice resistant gelatin capsules and a process for the production thereof
Patent #: 3959540
Issued on: 05/25/1976
Inventor: Leiberich ,   et al.

Pharmaceutical composition of prolonged action containing bile acids
Patent #: 4263272
Issued on: 04/21/1981
Inventor: Frigerio

Pharmaceutical formulations of acid labile substances for oral use Patent #: 4853230
Issued on: 08/01/1989
Inventor: Lovgren ,   et al.

Inventors

Application

No. 861462 filed on 04/01/1992

US Classes:

424/456, Gelatin424/464, Tablets, lozenges, or pills424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490Coated (e.g., microcapsules)

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

International Class

A61K 009/64

Foreign Application Priority Data

1991-04-12 IT

Abstract

Controlled release pharmaceutical formulations for oral administration coated by an enterosoluble gastroresistant film, preferably selected from gastroresistant granulates, gastroresistant tablets, gastroresistant hard gelatine capsules containing powders or granulates or two or more tablets or oily suspensions, gastroresistant soft gelatine capsules containing oily suspensions and hard gelatine capsules containing gastroresistant granulates or two or more gastroresistant tablets, containing therapeutically effective amounts of a mixture of bile acids and their salts with alkali metals or organic bases, process for their preparation and therapeutic use thereof in the treatment of biliary calculoses, biliary dyspepsias, biliary cirrhosis and chronic and cholestatic hepatopathies.

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