Topical drug delivery with polyoxyalkylene polymer thermoreversible gels adjustable for pH and osmolality
Patent 5298260 Issued on March 29, 1994. Estimated Expiration Date: 
June 9, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 9, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2674619 2677700 2979528 3036118 3535307 3639575 3740421 3829506 3867533 Osmotic drug delivery system InventorsAssigneeApplicationNo. 895949 filed on 06/09/1992US Classes:424/486, Synthetic polymer514/944, GEL516/102, The organic material contains organic compound containing nitrogen, except if present solely as NH4+516/104, The organic material contains organic compound containing oxygen523/105, Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel523/122Composition having ingredient providing biocidal or biostatic protection thereto or process of preparingExaminersPrimary: Webman, Edward J.Attorney, Agent or FirmInternational ClassesA61K 009/10A61K 047/34 AbstractIso-osmotic, hyperosmotic, or hypo-osmotic, pH balanced, thermoreversible gels are ideal medical devices or vehicles for drug delivery to the skin of a mammal. The osmolality in the gel state can be calculated by assuming that a polyoxyalkylene block copolymer or polyether present in said gel does not contribute to the osmolality in the gel state, although it does contribute to the measured osmolality in the liquid state.Other References
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