U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Gel composition for reduction of gingival inflammation and retardation of dental plaque

Patent 5298237 Issued on March 29, 1994. Estimated Expiration Date: Icon_subject January 24, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2470906

3065139

3886265

Oral hygiene compositions
Patent #: 3992519
Issued on: 11/16/1976
Inventor: Hofmann ,   et al.

Toothpaste active against plaque comprising a copper compound and a silica polishing agent
Patent #: 4332791
Issued on: 06/01/1982
Inventor: Raaf ,   et al.

Toothpaste active against plaque comprising a copper compound and a plastic polishing agent
Patent #: 4339429
Issued on: 07/13/1982
Inventor: Raaf ,   et al.

Preparation for oral hygiene
Patent #: 4622220
Issued on: 11/11/1986
Inventor: Frosch

Methods and compositions for treating dental structures
Patent #: 4652444
Issued on: 03/24/1987
Inventor: Maurer

Method and compositions for treating dental structures
Patent #: 4708864
Issued on: 11/24/1987
Inventor: Maurer

Preparation for oral hygiene
Patent #: 4719100
Issued on: 01/12/1988
Inventor: Frosch

More ...

Inventor

Application

No. 826482 filed on 01/24/1992

US Classes:

424/49, DENTIFRICES (INCLUDES MOUTH WASH)424/630, Copper424/638, With added organic compound514/474, Ascorbic acid or derivative (e.g., vitamin C, etc.)514/900, Periodontitis514/902, Gingival514/944GEL

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

International Classes

A61K 007/16
A61K 031/375
A61K 033/34

Abstract

The present invention provides a gel composition useful for the prevention or treatment of gingivitis, periodontal disease, and dental plaque which comprises ascorbic acid, copper sulfate, and essentially no added oxidizing agent, in concentrations sufficient for the prevention or treatment of gingivitis, periodontal disease, and dental plaque; and a gel carrier. The invention also provides a method for the prevention or treatment of gingivitis, periodontal disease, and dental plaque in the oral cavity of a subject which comprises applying for an effective period of time within the oral cavity of a subject an amount of the gel composition effective to prevent or treat gingivitis, periodontal disease, and dental plaque.

Other References

  • Barron, E. S. G., et al., Journal of Biological Chemistry, (1936), vol. 112, pp. 625-640 (Exhibit F)
  • Ball, E. G., Journal of Biological Chemistry, (1937), vol. 118, pp. 219-239 (Exhibit G)
  • Mystkowski, E. M., Biochemical Journal, (1942), vol. 36, pp. 494-500 (Exhibit H)
  • Ericsson, Y., Acta Pathologica Et Microbiologica Scandinavica, (1954), vol. 35, pp. 573-583
  • Berghagen, N., et al. Svensk Tandlakare-Tidskrift (1954), vol. 47, pp. 409-418
  • Ericsson, Y., Acta Pathologica Et Microbiologica Scandinavica (1955), vol. 37, pp. 493-506
  • Ericsson, Y., Acta Pathologica Et Microbiologica Scandinavica, (1955), vol. 37, pp. 507-527
  • Wade, A. B., et al. British Dental Journal, (1961), vol. III, pp. 280-285
  • Muller, E., et al., Helvetica Odontologica Acta, (1962), vol. 6, pp. 42-45
  • Kristoffersen, T., Odontologisk Tidskrift, (1963), vol. 71, pp. 179-198
  • Johansen, J. R., et al., Acta Odontologica Scandinavica, (1970), vol. 28, No. 5, pp. 661-67
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