U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Treating aids and HIV infection with methionine

Patent 5292773 Issued on March 8, 1994. Estimated Expiration Date: Icon_subject March 2, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Fortification of foodstuffs with N-acyl derivatives of sulfur-containing L-amino acid esters
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Inventor: Damico ,   et al.

Method of treatment of rheumatoid arthritis
Patent #: 4315028
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Apparatus and process for cooling a plasma arc electrode
Patent #: 4902871
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Antioxidant compositions and methods for ameliorating inflammatory symptoms of respiratory disease
Patent #: 4927850
Issued on: 05/22/1990
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Treating inflammatory pain with methionine
Patent #: 5053429
Issued on: 10/01/1991
Inventor: Hirsch, et al.

Methods for inhibiting inflammatory ischemic, thrombotic and cholesterolemic disease response with methionine compounds Patent #: 5084482
Issued on: 01/28/1992
Inventor: Hirsch, et al.

Inventors

Application

No. 845157 filed on 03/02/1992

US Classes:

514/554, Amine addition salt of the acid514/561, Nitrogen other than as nitro or nitroso nonionically bonded514/562, Sulfur nonionically bonded514/579Nitrogen containing other than solely as a nitrogen in an inorganic ion of an addition salt, a nitro or a nitroso DOAI

Examiners

Primary: Nutter, Nathan M.

Foreign Patent References

  • 9109524 EP. 07/13/1991
  • 0519876 EP. 12/13/1992
  • 2821704 DE. 11/13/1978
  • 3707127 DE. 09/13/1988
  • 9112809 WO. 09/13/1991

International Classes

A01N 037/30
A01N 037/12
A01N 037/44
A61K 031/13

Abstract

This invention concerns novel safe compositions containing as an active antioxidant or antiinflammatory agent and thiol-repleting agent, the amino acid methionine, and/or one or more related compounds including certain metabolic precursor compounds, and novel methods employing the compositions for treating or amelio-rating symptoms of human immunodeficiency virus infection and AIDS, such as weight loss, increased red cell sedimentation, and leukoplakia; novel methods employing the compositions for treating or inhibiting symptoms resulting from nutritional deficiencies of methionine; and novel methods employing the compositions for inhibiting or preventing triglyceride elevation due to low dose methionine consumption. The compounds include the methionine hydroxy analogs, as well as compounds having the structural formula ##STR1## 1-, dl- or d- form and pharmaceutically acceptable N- (mono- and di-carboxylic acid) acyl derivatives and alkyl esters thereof.

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